4Life Research Transfer Factors Explained in 8 Minutes (English)
Natural Killer cells, or NK cells, are important immune cells that provide a crucial first defense against infectious agents and diseased cells. Once activated, NK cells react in two ways. First, they promptly secrete chemical messenger proteins that modulate emerging immune cell responses. Second, they become potent killers of infected cells. Without Natural Kill cells, threatening conditions can get a strong foothold before additional immune responses are able to kick in.
4Life Research Announces New Discovery - NanoFractions
The above chart shows the results of a study conducted by Jeunesse Inc., Institute of Longevity Medicine. This study examined the ability of nutrients to increase the effectiveness of the immune system's natural killer cells. 196 of the world's most popular nutrients were tested. These nutrients were tested in blood in the presence of live cancer cells.
Original test results showed that 4Life Transfer Factor Classic boosted NK cell activity 103% above normal immune response without supplementation, more than two times higher than the next highest product.
Studies conducted by the Russian Academy of Medical Science validate these original results and report that 4Life Transfer Factor Advanced Formula boosts NK cell activity by 283% and 4Life Transfer Factor Plus Advanced Formula propels NK cell activity to a remarkable 437% above normal immune response! Studies also showed that 4Life Transfer Factor Classic increased NK cell activity by 204% when tested at a 48-hour activation time. The NK cells is the animal's first line of defense against many pathogens...bacteria, viruses, parasites, and of course malignant tumor cells.
For a more complete description of this study, click here.
*Test results obtained from two independent NK cell studies. Original test using 4Life Transfer Factor Classic bovine formula utilized a four-hour activation time. Secondary blind study test results, conducted by Dr. Anatoli Vorobiev, head of Immunology, at the Russian Academy of Medical Science, used 4Life Transfer Factor Advanced Formula (Transfer Factor E-XF proprietary blend of both cow colostrums and egg yolk sources) and a 48-hour activation time. Comparison of activation times demonstrated that the longer activation time (48 hours) using the 4Life Classic and Advanced Formulas promoted a significantly greater percentage increase of NK cell response. Samples were tested for maximum time of effectiveness.
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With two products—4Life Transfer Factor Classic and 4Life Transfer Factor Plus—that already set new and higher standards in immune system support—providing boosts in Natural Killer (NK) cell activity of 103 and 248 percent—how did 4Life think of trying to improve them? It started with a dedication to the long-term pursuit of transfer factor research, which led to the discovery of eggs as another viable source for transfer factors. A commitment to remain the leader in transfer factor technology and to provide the highest quality, most effective products for good health further drove 4Life to be even better. And finally, it came from the belief that one of the best ways to improve 4Life Transfer Factor was to broaden the spectrum of support by combining safe and effective sources of transfer factors.
4Life researchers and scientists developed the Transfer Factor E-XF™ proprietary blend in an effort to further maximize immune system support using transfer factor molecules. Transfer factors were taken from both the cow and chicken sources and combined in hopes of sparking a synergistic–effect which was definitely achieved.
4Life Transfer Factor Advanced Formula and 4Life Transfer Factor Plus Advanced Formula both feature the scientifically proven Transfer Factor E-XF proprietary blend. Developed exclusively by 4Life using patented and patent-pending technology, the E-XF blend calls upon the knowledge of two sources, providing an enhanced combined effect of transfer factors from both cow colostrum and chicken eggs. Research shows that the immune building effects of this transfer factor blend are more effective than that of colostrum or egg sources alone.
In an effort to determine how powerful the 4Life Transfer Factor Advanced formulas are, researchers Calvin McCausland, Ph.D and Emma Oganova, Ph.D, M.D. designed a study to test NK cell activity. Dr. Anatoli Vorobiev at the Russian Academy of Medical Science directed his team in the independent testing. Using blinded cytotoxicity testing, cancerous cells were combined with NK cells from humans and divided into groups of NK cells activated with transfer factors and groups of unactivated NK cells.
Samples containing several different blends of transfer factors sourced from cow colostrum and egg yolks were incubated with the NK cells for various time periods, in order to identify the most potent blend ratio and the optimal activation time of NK cells to provide maximum health benefits. Comparison of times demonstrated that the activation time of 48 hours promoted the greatest NK cell response.
Results of this study conclusively demonstrated the ability of 4Life Transfer Factor Advanced Formula to boost NK cell activity by 283 percent and of 4Life Transfer Factor Plus Advanced Formula to propel NK cell activity to a remarkable 437 percent above normal immune response (a response established as a baseline from this study). They also showed that 4Life Transfer Factor Classic increased NK cell activity by 204 percent when tested at a 48-hour activation time. Further, results from this scientific experiment showed that NK cells activated with 4Life Transfer Factor Plus Advanced Formula killed 97 percent of cancerous cells, which exceeded the Interleukin-2 (IL2) activation kill rate of 88% during the same time period.
The Russian scientists who conducted this study found the results to be exceptional and requested further information so their results could be published in professional journals. One scientist stated: “The 4Life sample [4Life Transfer Factor Plus Advanced Formula] activated NK cell activity more than the Interleukin-2 (IL2) drug used as the standard. Here, we now refer to your sample as the Golden Interleukin,” said Dr. Kisielevsky, Russian Academy of Medical Sciences.
These outstanding test results are certain to be reflected in human health through an increase in immune effectiveness, leading to improved overall health. People around the world can be confident in the ability of 4Life Transfer Factor Advanced Formula and 4Life Transfer Factor Plus Advanced Formula to more effectively modulate immune system function, making it more response “able” and to provide broad-spectrum support that is unmatched in any other health supplement today.
4Life Research Announces New Discovery - NanoFractions
September 21, 2007 (Salt Lake City, Utah) 4Life Research™, the world leader in Transfer Factor science and immune system support development, announced today the discovery of immune activity in a weight range of molecules significantly smaller than transfer factors.
Transfer factors are molecules in a weight class between 3,500 - 12,000 daltons that help the immune system recognize, respond to, and remember outside threats. Although scientists have known that smaller molecules than transfer factors existed within cow colostrum, their significance in terms of immune activity has been unknown until now.
In 2005, 4Life Chief Executive Officer David Lisonbee and the Research and Development department began studying these low weight molecules. After two years of research, 4Life clinical findings now indicate that molecules in a weight range between 250 — 3,000 daltons play important regulatory roles in the immune system.
4Life extracted and concentrated these nanofraction molecules from cow colostrum for their proprietary NanoFactor™ extract, combining NanoFactor with their exclusive Transfer Factor E-XF™ extract of transfer factors from cow colostrum and chicken egg yolks to produce 4Life Transfer Factor® Tri-Factor™ Formula, the most comprehensive approach to immune system support available today.
"I don't know of another company in our category," said 4Life Chief Scientific Officer Calvin McCausland, Ph.D. "In 2004, we were the first company to combine transfer factors from cow colostrum and chicken egg yolks. In 2005, we introduced RioVida®, the world's only transfer factor beverage. Now, the discovery of new immune activity in nanofractions. When it comes to scientific innovation, there's simply no comparison to 4Life."
4Life Transfer Factor, Transfer Factor Plus®, and RioVida are now fortified with the new Tri-Factor Formula. "We're taking Tri-Factor Formula to the world because no other product represents such a unique and indispensable opportunity for a quality life," remarked 4Life President Steve Tew.
David Lisonbee: "At the end of the day, our distributors can rest assured that 4Life will stay a good pace ahead of the curve in the areas of science, service, and success."
4Life, global leader in the development, production, and distribution of Transfer Factor immune support products, continues to post growth in more than 40 countries around the world.
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What we now know in the 21st century about our complex immune system is changing the way we perceive and treat disease. Especially what we are now beginning to understand about how very important our Natural Killer Cells (NK) are in keeping us alive and well.
What we’ve learned has already had a profound effect on the health and wellness of many of the patients in clinical practices around the globe. We previously know that Natural Killer Cells normally kill virus or bacteria independently. What we didn’t realize is that these cells are often inactive and not functioning as necessary or in the manner needed to maintain optimum health.
Physicians can now measure patients Natural Killer Cell Activity Function as well as the Natural Killer Cell Count. Most of us have enough Natural Killer Cells (i.e. our counts are typically normal); however, many of us do not have enough Natural Killers that are active. These inactive NK cells are present in great numbers in our blood, lymph nodes, organs and tissue, but they are not killing foreign invaders such as infectious organism and malignant cells that constantly affect all of us.
Fortunately we can take a safe, highly effective *natural supplement that has been proven to consistently and dramatically increase the activity of many of our own Natural Killer Cells.
Almost all cancer patients have very low levels of Natural Killer (NK) Cell Activity: usually 0 to 20. Many patients with chronic diseases including fibromyalgia and chronic fatigue syndrome, as well as a wide variety of autoimmune disorders including rheumatoid arthritis, lupus, multiple sclerosis and others, also have low levels in the 10 to 30 ranges.
Most patients with chronic and/or recurrent infections (such as staph, sinusitis, bronchitis, tonsillitis, pneumonia and ear infections, etc.) have low levels in the 10 to 50 ranges. Many patients with symptomatic EBV, CMV, HPV and other chronic viral infections are in the 0 to 20 ranges.
Some healthy patients have been in the 150 to 250 ranges, but most others fall in the 50 to 150 range. Some supposedly “healthy” patients have had a very low NK Cell activity between 0 to 10. It is now known that low NK Cell activity is significant independent risk factor for the future development of cancer as well as other chronic diseases and illnesses.
It is also known that low NK Cell activity is a strong predictor or poor prognosis of survival of cancer patients. But it is also known that the higher the NK Cell activity in patients with cancer, the better their prognosis is for survival.
In addition, it is known that there is a direct age related decrease in NK Cell activity from 20 to 80 years of age, which may partially explain why the risk of cancer increases with each decade of life.
- People of all ages desire to prevent acute and chronic diseases. It would be good for all of us and for our families to do everything possible to elevate and reactivate our Natural Killer Cells.
Over 3000 clinical studies have so far been published on the molecule transfer factors.
This information sheet has been prepared with enough data for you to determine for yourself that Transfer Factor is a powerful, effective product you would be proud to recommend to others.
Transfer Factor Plus has been independently and scientifically found to be more than 5 times more powerful than any other natural product yet discovered.
For Long-term and solid success, you must have a product that really helps people.
1999 Independent Study by the Institute of Longevity Medicine
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According to Dr. George C Pack, MD, a cancer specialist at Cornell medical School, almost everyone has cancer cells present at times in our bodies. If our immune system is working properly, these cells are killed or reabsorbed by our defense system before they begin to grow and threaten our health. The only real defense against cancer is the immune system.
The Cancer Research Institute was founded in 1953 to foster the science of cancer immunology, which is based on the premise that the body's immune system can be mobilized against cancer. This field, which CRI helped pioneer and develop, has been recognized throughout the world as offering great hope for the ultimate prevention and treatment of human cancer. Click here to read about The Cancer Research Institute's articles on Cancer and the immune system
The immune response is the body's way of defending itself against foreign substances that invade it to cause infection or disease. The immune system's job is a complicated process that involves the coordinated efforts of several types of white blood cells. The pictorial below depicts the process by showing how the immune system destroys viruses.
See our special report on Cancer and the Immune system: How the body Kills Cancer Cells.
Trials with Transfer factor and Cancers
Darryl See, M.D. conducted the following studies after his initial trial showed the awesome immune boosting qualities of Transfer factor.
The initial results of a groundbreaking independent study using Transfer Factor™ and Transfer Factor Plus™ yielded unprecedented results in a study done by the Institute of Longevity Medicine in California, a laboratory recognized for its research and expertise in measuring the ability of ingredients to significantly boost the immune system. Dr See had showed that Transfer Factor Plus™ increased the NK cell activity 248% above normal immune response without supplementation, or about five times higher than any of the other 196 previously tested products. This is higher than any other drug, vitamin, herb, etc.
In the follow up research, twenty patients, 12 men and 8 women, were selected for this in vivo study. The average age was 49.3. The twenty individuals were each level 3 or level 4 cancer patients. Each patient was basically sent home by his or her oncologist to die. The average life expectancy was 3.7 months. The protocol was to place each patient on 9 capsules per day of Transfer Factor Plus. The patients were given a number of other general nutrients*. After eight months, 16 of these individuals were still living and were either in remission, improving or stabilized. Details: Transfer Factor Study with 20 Cancer Patients
The baseline for natural killer cell function was 6.4. Within 4 weeks the average NK Cell function was increased to 25.7 and in 6 months it increased to 27.6. This represented a 400% increase in NK Cell function. This is an ongoing study. This study has been submitted to a peer reviewed publication.
May 2004: The New Advanced Formula Transfer Factor+ further improves on the Classic Formula. Combines Bovine and Chicken Transfer Factors. Raises NK cell activity by 437%.
Natural Killer cells, or NK cells, are important immune cells that provide a crucial first defense against infectious agents and diseased cells. Once activated, NK cells react in two ways. First, they promptly secrete chemical messenger proteins that modulate emerging immune cell responses. Second, they become potent killers of infected cells. Without Natural Kill cells, threatening conditions can get a strong foothold before additional immune responses are able to kick in.
Disclaimer:
The Information in this site is provided for educational purposes only. It is not intended to rely upon for diagnosis or treatment of any disease or medical condition. Seek advice from your health care professional regarding the applicability of any information, opinion or recommendation for diagnosis or treatment of any symptoms or medical condition. Statement and testimonies about products and health conditions have not been evaluated by the Food & Drug Administration. They are not intended to rely upon for diagnosis or treatment of any disease or medical condition. The testimonies and information on this website only represent the opinions of the individuals involved. The accuracy of each testimony has not been verified. We encourage you to use common sense in your expectations in consuming any nutritional product. Keep in mind that some of these statements and testimonies come from distributors of these products and may have a conflict of interest. It is not suggested that anyone should replace traditional medical treatment with Products of 4Life Research. They are not intended to treat, cure, or prevent any disease.Disclaimer:
